Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). Hepatitis B is a major global health problem that causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer (1). Hepatitis B virus is a partially double stranded DNA virus which belongs to Genus Orthohepadnavirus of family Hepadnaviridae (2). According to WHO estimation 296 million people were living with chronic hepatitis B infection in 2019, with 1.5 million new infections each year while 820000 deaths due to Liver cirrhosis and hepatocellular carcinoma (primary liver cancer) caused by Hepatitis B virus [1]. The hepatitis B virus (HBV) is transmitted through blood and infected bodily fluids. It can be passed to others through direct contact with blood, unprotected sex, use of illegal drugs, unsterilized or contaminated needles, and from an infected woman to her new born during pregnancy or childbirth (3). Hepatitis B symptoms are Abdominal pain, Fever, joint pain, loss of appetite, Weakness fatigue, yellowing of skin and the whites of your eyes(4).